Journal: Biomedical microdevices
Article Title: 3D printed transwell-integrated nose-on-chip model to evaluate effects of air flow-induced mechanical stresses on mucous secretion
doi: 10.1007/s10544-021-00602-y
Figure Lengend Snippet: Overview Schematic for Chip Design and Transwell Preparation. A) 3D printed lab-on-chip device with three internal chambers to house transwell inserts, flow channel for gas delivery, lid to guard against contamination, and inlet/outlet nozzles to connect tubing apparatus. B) 3D printed mold for transwells supports. The 3-part mold comprises two mirrored portions to define outer well walls and dowels to form inner cylindrical well openings. C) Three custom PDMS transwells are inserted into the 3 slots of the chip device. D) Transwell fabrication process. E) Procedure for adding cells to transwell
Article Snippet: The chip device was affixed to a sliding panel with a custom 3D printed mount, designed with AutoDesk Inventor and built on a MakerBot Replicator 2 printer using polylactic acid (PLA).
Techniques: Lab-on-a-Chip